This report analyzes the effect of US immigration policies on migrants and residents along the US-Mexico border. It begins with a discussion of US border enforcement strategies and expenditures. It describes the multifaceted impact of these policies on migrants, their families, and border residents. In addition, it details the inequities and burdens caused by the prosecution of immigration violations, the nation’s need for immigrant laborers, the exploitation of immigrants in many industries, and their living conditions. It also describes work at the “maquiladoras,” the foreign-owned assembly plants in Mexico. It ends with recommendations on potential policy solutions.